Regular intake of omega-3 supplements increases the risk of heart disease.
Is daily omega-3 intake truly beneficial for the heart? A recent large-scale longitudinal study suggested a link between regular omega-3 intake and an increased risk of heart disease. This article explores who benefits from omega-3 and who may be at risk, what choices are needed to avoid increased heart disease risk, and provides tips for safe intake and dietary alternatives. This article provides a comprehensive overview of the issue of omega-3 and increased heart disease risk.

Research at a glance

Researchers from the United States, the United Kingdom, Denmark, and China tracked approximately 410,000 people aged 40 to 69 for an average of 12 years using data from the UK Biobank. Thirty-one percent of respondents reported regularly taking omega-3 supplements, and during that period, they identified approximately 22,000 cases of heart attack, stroke, heart failure, 18,000 cases of atrial fibrillation, and 22,000 deaths.
The analysis found that regular users had a roughly 13 percent higher risk of atrial fibrillation and a 5 percent higher risk of stroke than non-users. Even after accounting for other variables, such as age, gender, smoking, and high blood pressure, the trend persisted. The study, published in BMJ Medicine, is notable for being the first to demonstrate a negative association using long-term data.
Background of increased risk of heart disease

Researchers explain that omega-3s can affect the heart's electrical rhythm. Specifically, alterations in the conduction properties of the atria can trigger atrial fibrillation. For this reason, the American Heart Association does not recommend regular preventive omega-3 supplementation. Instead, they recommend prioritizing dietary intake and lifestyle changes.
Another picture of a pre-existing condition
Interestingly, different signals were observed in people with pre-existing cardiovascular disease. The risk of progression from atrial fibrillation to myocardial infarction was approximately 15 percent lower, and the risk of progression to heart failure was approximately 9 percent lower. Therefore, while there may be benefits in the context of treatment, tailored application is necessary under the discretion of the medical professional.
- healthy person Regular use increases the risk of atrial fibrillation by about 13 percent.
- healthy person About a 5 percent increase in stroke risk
- Patients with existing medical conditions Reduced risk of developing myocardial infarction by approximately 15 percent
- Patients with existing medical conditions Reduced risk of heart failure progression by approximately 9 percent
- Common Results may vary depending on individual condition and concomitant medications.
Which choice is wise for whom?

Healthy adults without specific indications are advised not to habitually take omega-3 supplements. For medical purposes, such as treating hyperlipidemia, consult your doctor to determine the dosage and formulation. Taking high doses can increase the risk of side effects, and regular monitoring is essential to determine the need for supplementation and when to discontinue use.
- Health checkup confirmation Check your family history for atrial fibrillation and electrocardiogram abnormalities
- Check your medication list Caution when taking anticoagulants or antiplatelet agents
- Capacity Management Do not exceed the recommended daily dose of the product. Do not take in high doses.
- Check the ingredients Check EPA DHA content and raw material origin
- abnormal signal If palpitations, dizziness, or shortness of breath occur, stop immediately and seek medical advice.
- Reevaluation cycle Check the effectiveness and side effects with your doctor every three months.
Omega-3s from the diet and alternative strategies
A diet centered on vegetables, fruits, whole grains, beans, nuts, and olive oil, like the Mediterranean diet, is beneficial for heart health. Eating blue-backed fish like mackerel, salmon, sardines, and herring twice a week can naturally supplement your omega-3 intake. Perilla oil, flaxseed, and walnuts are also good choices.
Practical tips: Cook refrigerated fish while it's still fresh, either by grilling or steaming, and avoid over-frying. When choosing canned fish, check the sodium content and choose products made with water or olive oil. Pregnant women and children should reduce their consumption of large fish to manage heavy metal exposure.
Frequently Asked Questions

Should I stop taking Omega 3 right away?
If you're taking it solely for health reasons without a specific reason, you may consider discontinuing. However, this decision depends on your individual risk and whether or not you're taking the medication, so consult with your healthcare provider. If you're taking it for therapeutic purposes, follow your doctor's instructions rather than discontinuing on your own.
How much should I eat per day to be safe?
The required dosage and formulation vary depending on the intended use and medical condition. Do not exceed the daily intake recommended on the product label, and use higher doses only under medical supervision. Increasing the dosage without prior notice may increase the risk of side effects.
Can you fill it with just fish?
Eating oily fish twice a week is sufficient for most people. Adding walnuts, flaxseed, or perilla oil to this mix improves balance. A food-based diet benefits greatly from the synergy of other nutrients.
Can I take it with other medications?
When used in combination with anticoagulants or antiplatelet agents, bleeding risk management is necessary. If you are scheduled for surgery or have a history of arrhythmia, be sure to discuss taking this medication with your doctor. Even with health functional foods, interactions can occur.
What should I do if I feel dizzy or lightheaded?
If you experience symptoms such as palpitations, chest tightness, dizziness, or fainting, stop taking the medication immediately and seek medical attention. Early detection and treatment of atrial fibrillation are crucial. If you experience emergency symptoms, seek help without delay.
Key Summary: First, consistent intake of omega-3s in healthy individuals is associated with an increased risk of heart disease, including atrial fibrillation and stroke. Second, patients with existing cardiovascular disease show signs of reduced risk of progression, requiring personalized medical advice. Third, a diet-based approach is essential, with supplements being the exception, and careful selection is crucial.
The wise path to using omega-3 begins with understanding your body's condition. Develop a strategy tailored to you through regular checkups and expert consultations, prioritizing your diet and lifestyle. Always maintain a balanced perspective on the issue of omega-3 and increased risk of heart disease.